The DNA Vaccine Response Test (Vaccinomics Panel) analyzes your genetic predisposition to immune responses triggered by four important vaccines: influenza, hepatitis B, measles-mumps-rubella (MMR), and smallpox. This test provides insight into how effectively your immune system may respond to vaccinations — supporting personalized vaccine guidance and long-term health protection.

Your genetic response to vaccines is influenced by multiple immune-related genes that regulate antigen presentation, cytokine signaling, and antibody production. This test examines those genes to determine how likely you are to generate a strong, moderate, or weak immune response to specific vaccines.

For influenza, the test evaluates how well your immune system is genetically equipped to neutralize viral infection and benefit from annual flu shots. Even with low risk, annual vaccination and hygiene practices are still recommended, as the flu virus mutates frequently.

For MMR (measles, mumps, rubella), the test supports whether your immune system is likely to mount a strong defense post-vaccination. Though most people are vaccinated in childhood, this insight helps guide booster decisions and informs risk for future exposure or outbreaks.

The smallpox vaccine response is also covered, despite the disease being eradicated. In high-risk or military settings where smallpox vaccination may still be considered, this genetic insight can support risk assessment.

The most important marker in this test is hepatitis B vaccine response. A moderate or poor genetic response may indicate a need for additional boosters, antibody titer monitoring, or alternative dosing strategies. Since hepatitis B is spread through blood and bodily fluids and can lead to liver cancer, understanding your immune response is critical — especially for healthcare workers, travelers, or individuals with high-risk exposure.

Each result includes a polygenic risk score (PRS), with recommendations based on whether you fall into low or moderate risk categories. The test does not replace vaccination but enhances decision-making by revealing how your body may react to each immunization.

The DNA Vaccine Response Test is ideal for individuals looking to personalize vaccine plans, improve travel health safety, support workplace immunity requirements, or optimize preventive care based on how their immune system works at the genetic level.